水溶性苝系衍生物荧光探针的合成及对金属离子的识别

Synthesis of Fluorescence Probe Based on Water SolublePerylene Derivatives and Its Recognition of Metal Ions

摘要: 用苝四酸酐为反应物，在酸酐位置上引入天冬氨酸，合成了水溶性的含4个羧基的荧光苝二酰亚胺衍生物：N,N'-二天冬氨酸铵盐-3,4,9,10-苝四羧酸二酰亚胺（PTCDA）.在水溶液中与Fe³⁺、Al³⁺、Pb²⁺和Cu²⁺等金属离子反应，吸收光谱发生红移，荧光淬灭.当加入等量Hg²⁺、Zn²⁺、Ni²⁺、Co²⁺、Mn²⁺和Mg²⁺等金属离子后不干扰荧光反应，有选择性好、灵敏度高等特点.并探讨了衍生物的荧光反应机理，表明有好的应用价值和广阔发展前景.

Abstract: A water-soluble fluorescent perylene diimide derivative with four carboxylic groups N,N′-bi(L-aminosuccinic amine)-perylene-3,4;9,10-tetracarboxylic diimide was synthesized using L-Aspartic acid and 3,4;9,10-perylenetetracarboxy anhydride. Red shift of the spectra was observed and the fluorescence of compound was quenched in the presence of Fe³⁺、Pb²⁺、Al³⁺ and Cu²⁺ metal ions，while the quenching of fluorescence was weak in the presence of Hg²⁺、Zn²⁺、Ni²⁺、Co²⁺、Mn²⁺ and Mg²⁺. There is no other anions to interference the detection．The fluorescence mechanism of PTCDA was discussed and the results showed that this method is worth of application and has a broad prospect.