Abstract: In order to optimize the microwave extraction conditions of polysaccharides from Bauhinia championii Benth, different factors affecting the extraction efficiency, such as the extraction time, solid-liquid ratio, microwave power, extraction temperature, were selected as the levels of single factor. The single factor and orthogonal tests were used to investigate the optimal microwave extraction conditions indicated by the total peak areas of monosaccharide in the hydrolyzed saccharides from Bauhinia championii Benth polysaccharide using CE equipped with a UV detector. The experiment results showed that the microwave power has the greatest impact on extraction efficiency, followed by the extraction temperature, extraction time and solid-liquid ratio. Therefore, the optimal macrowave power, extraction temperature, extraction time and solid-liquid ratio were 600 W, 70 ℃, 25 min, 1∶35, respectively.