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离子色谱法在中药化学成分分析中的应用进展

颉东妹 魏晗婷 王宁丽 刘建飞 郭玫 邸多隆

颉东妹, 魏晗婷, 王宁丽, 刘建飞, 郭玫, 邸多隆. 离子色谱法在中药化学成分分析中的应用进展[J]. 分析测试技术与仪器, 2022, 28(2): 179-187. doi: 10.16495/j.1006-3757.2022.02.012
引用本文: 颉东妹, 魏晗婷, 王宁丽, 刘建飞, 郭玫, 邸多隆. 离子色谱法在中药化学成分分析中的应用进展[J]. 分析测试技术与仪器, 2022, 28(2): 179-187. doi: 10.16495/j.1006-3757.2022.02.012
XIE Dong-mei, WEI Han-ting, WANG Ning-li, LIU Jian-fei, GUO Mei, DI Duo-long. Application Progress of Ion Chromatography in Analysis of Chemical Components of Traditional Chinese Medicine[J]. Analysis and Testing Technology and Instruments, 2022, 28(2): 179-187. doi: 10.16495/j.1006-3757.2022.02.012
Citation: XIE Dong-mei, WEI Han-ting, WANG Ning-li, LIU Jian-fei, GUO Mei, DI Duo-long. Application Progress of Ion Chromatography in Analysis of Chemical Components of Traditional Chinese Medicine[J]. Analysis and Testing Technology and Instruments, 2022, 28(2): 179-187. doi: 10.16495/j.1006-3757.2022.02.012

离子色谱法在中药化学成分分析中的应用进展

doi: 10.16495/j.1006-3757.2022.02.012
基金项目: 

甘肃省重点研发计划 2021-0202-NCC-0163

甘肃省青年科技基金计划 20JR10RA054

甘肃省科技计划项目 21YF5NA135

甘肃省科技计划项目 21CX6NF234

详细信息
    作者简介:

    颉东妹(1996-), 女, 硕士研究生, 研究方向: 中药学, E-mail: 416174332@qq.com

    通讯作者:

    郭玫,女,教授,研究方向:中药药效物质基础与质量标准研究,E-mail: guomei@gszy.edu.com

    邸多隆,男,研究员,《分析测试技术与仪器》副主编,研究方向:分析化学,E-mail: didl@licp.cas.cn

  • 中图分类号: O657.7+5;R284.1

Application Progress of Ion Chromatography in Analysis of Chemical Components of Traditional Chinese Medicine

Funds: 

Key Research and Development Program of Gansu Province 2021-0202-NCC-0163

Gansu Province Youth Science and Technology Fund program 20JR10RA054

Science and Technology Plan Project of Gansu Province 21YF5NA135

Science and Technology Plan Project of Gansu Province 21CX6NF234

  • 摘要: 离子色谱作为一种新型高效液相色谱技术, 最初主要应用于测定样品中的阴阳离子含量, 如今发展为应用于有机酸、生物胺、糖类等化合物的组成及含量测定. 离子色谱法具有操作简便、灵敏度高以及选择性好等优点, 因此, 目前离子色谱法已在能源、环境、地质、食品、药物等领域得到了广泛应用. 总结了近年来离子色谱在中药金属离子、无机阴离子、有机酸、糖类成分的研究进展, 为离子色谱法分析中药化学成分提供了参考.
  • 表  1  IC在化学成分分析中的应用

    Table  1.   Application of IC in analysis of chemical components

    来源 化学成分 色谱柱类型 参考文献
    瓜蒌皮注射液 Cl-、Na+、NH4+ IonPac AS11-HC、IonPac CS12A [7]
    丹参 Li+、K+、Mg2+、Ca2+ IonPac CS12A [8]
    女贞子 Na+、K+、Mg2+、Ca2+ IonPac CS12A [9]
    萹蓄 K+、Mg2+、Ca2+ IonPac CS12A [10]
    40批中药制剂 SO2/SO42- Thermo Scientific [15]
    甘草、制天南星和金银花等 SO2/SO42- IonPac AS11-HC [16]
    西瓜霜 SO2/SO42- IonPac AS11-HC [17]
    臭灵丹 SO42-、PO43-、Cl-、NO3- Ion Pac AS22 [20]
    麻黄 SO42-、Br-、Cl-、NO2- Ion Pac AS22 [21]
    漱口药 F-、Cl-、SO42-、PO34-、单氟磷酸钠、甘油、山梨酸钾及糖精钠 Ion Pac AS18 [22]
    利咽灵片 F-、HCOO-、Cl-、NO2-、Br-、NO3-、SO24-、C2O24-和PO34- Ion Pac [23]
    木瓜、女贞子、金银花、覆盆子、山茱萸 乳酸、乙酸、甲酸、苹果酸、酒石酸、草酸、富马酸 IonPac AS11-HC [30]
    金丝梅、萝芙木 NO2-、SO42-、C2O24-、Cl- IonPac AS11 [31]
    注射用丹参 乳酸、乙酸、甲酸、琥珀酸、草酸 IonPac AS11-HC [32]
    糊精 葡萄糖、麦芽糖、麦芽三糖、麦芽四糖、麦芽五糖 Dionex CarboPac PA200 [36]
    乳制品 乳糖、半乳糖、葡萄糖、N-乙酰氨基葡萄糖 CarboPac PA1 [37]
    果胶 葡萄糖、半乳糖、甘露糖、鼠李糖、阿拉伯糖、木糖 CarboPac PA1 [38]
    玄参 水苏糖 METROSEP CARB 1 [39]
    芦荟 岩藻糖、鼠李糖、阿拉伯糖、半乳糖、葡萄糖、甘露糖、木糖 Dionex CarboPac PA10 [41]
    青钱柳 鼠李糖、阿拉伯糖、半乳糖、葡萄糖、甘露糖、木糖 Carbo PACTM PA10 [42]
    花黄精 鼠李糖、阿拉伯糖、半乳糖、葡萄糖、甘露糖、果糖 CarboPac PA1 [43]
    下载: 导出CSV
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出版历程
  • 收稿日期:  2022-03-03
  • 修回日期:  2022-04-14
  • 网络出版日期:  2022-07-07
  • 刊出日期:  2022-06-30

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