Abstract: 15 metals in traditional Chinese medicine and capsules were determined simultaneously by microwave digestion and inductively coupled plasma mass spectrometry(ICP-MS).Scandium and Indium were used as the internal standards. The results showed that the detection limits of the 15 metals were between 0.000 7~0.047 μg/g and all the relative standard deviations were less than 10%. The spiked recovery rates were between 82.3%~116%. The method can be effectively applied to the determination of aquatic products because of rapidness, high sensitivity and good reproducibility.