二维核磁共振技术解析盐酸帕罗西汀

Analysis of Paroxetine Hydrochloride Using 2D-Nuclear Magnetic Resonance

摘要: 报道了盐酸帕罗西汀的分子结构解析方法，利用国产核磁共振波谱仪测试了盐酸帕罗西汀核磁氢谱(¹H-NMR)、核磁碳谱(¹³C-NMR、DEPT 135°)、二维核磁相关谱(¹H-¹HCOSY、¹³C-¹H HSQC、¹³C-¹H HMBC)，实现了盐酸帕罗西汀氢碳的全部归属.

Abstract: The molecular structure analysis method of paroxetine hydrochloride was reported. The nuclear magnetic hydrogen spectrum (¹H-NMR), nuclear magnetic carbon spectrum (¹³C-NMR, DEPT 135°) and two-dimensional nuclear magnetic correlation spectrum (¹H-¹HCOSY, ¹³C-¹H HSQC, ¹³C-¹H HMBC) of paroxetine hydrochloride were measured on the domestic scientific instrument nuclear magnetic resonance spectrometer, and all the hydrogen and carbon of paroxetine hydrochloride were attributed.