Abstract: The conventional laboratory detection methods have become increasingly mature in the field of drug detection. The existing laboratory analysis methods can no longer meet the needs of on-site rapid drug detection, and it is urgent to develop portable drug detection technology and equipment. In some rapid detection methods, the application of portable devices has become widespread and is being continuously studied in depth. As a device with rapid identification for target substances, sensors can quickly identify suspicious items in drug detection. With the changes in the types of drugs and the continuous updating and iteration of drug types, the detection requirements for sensors have increased, so that different types and functions of sensors have emerged. In view of the sensor with easy operation, low cost and rapid analysis, the application of portable drug sensors are bound to become an important part of field detection, especially in the field of on-site detection. In recent years, with the demand-oriented research and the deepening of research content, some new drug detection technologies, materials and equipment have been successfully developed. With the feedback of measured information and the continuous optimization of equipment, the portable detection equipment for drugs will become a powerful means to fight against drug crimes.