Abstract: This review with 52 references offer an introduction to the instrumental character and new techniques of FT/ICR/MS. It deals with several ion dissociation techniques about ultraviolet photodissociation(UVPD), multiphoton infrared photodissociation(IRMPD), surface induced dissociation(SID), blackbody infrared dissociation(BIRD). The ion remeasurement technique that can improve dissociation efficiency was also discussed. They include sustained off resonance irradiation(SORI), very low-energy excitation(VLE), multiple excitation collisional activation(MECA), stored waveform inverse fourier transform(SWIFT). Finally, the applications of biological analysis and ion-molecule reaction were introduced.