Analytical Methods for Anticholinergic Trospium Chloride: A Review

Trospium chloride is one of anticholinergic medicines which can effectively relieve overactive bladder (OAB) with symptoms of urge incontinence and frequent micturition. Due to its higher tolerability, trospium chloride is safer to patients compared with other medicines. However,only a few articles on the analysis of trospium chloride and no relevant reviews are published till now. In this paper, the quantitative analytical methods for trospium chloride, including titration, UV spectrophotometry, HPLC, GC, and liquid scintillation counting (LSC), are reviewed with the prospacts of their developments.